Postfix (since 2.11), Exim (since 4.85), Sendmail (via patches), Halon, and PowerMTA. On the receiving side, deploying TLSA records is straightforward. On the sending side, most operators enable DANE checking in the smtpd config. Google Workspace + Microsoft 365 do not currently check DANE on outbound; they honor MTA-STS instead.
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